Mfuwe International Airport was opened in mid 70s as a domestic airport to service the South Luangwa National Game Park, which is one of the largest national game parks in Zambia. The airport gained its International status in 1995 when it was gazetted as a port of entry and exit. The airport serves over twenty lodges and campsites. It has a runway measuring 2.2 km long.

Its’ location in the middle of the South Luangwa National Park makes it convenient for flight connections to most tourist destinations in Zambia and in the region. There are daily flights from Lusaka to Mfuwe and direct flights from Mfuwe to Lilongwe. There are plans to provide for additional connections with other tourist destinations like Mombasa, Victoria Falls, Kariba, Harare and Johannesburg. The terminal building has a capacity to handle 100,000 passengers per year.